Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 AlteredExpression disease BEFREE Targeting high-sensitivity C-reactive protein levels in acute coronary syndrome patients undergoing contemporary lipid-lowering therapy: a sub-analysis of the HIJ-PROPER trial. 31699568 2020
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.150 Biomarker disease BEFREE Prognostic Value of Lipoprotein(a) Levels in Patients Undergoing Coronary Angiography for Premature Acute Coronary Syndromes. 31722547 2020
Entrez Id: 55902
Gene Symbol: ACSS2
ACSS2
0.100 Biomarker disease BEFREE We describe the incidence, timing, and characteristics of stent thrombosis and its consequences in patients with atrial fibrillation (AF) in the AUGUSTUS trial<sup>1</sup> who received a coronary stent during their qualifying admission (acute coronary syndrome [ACS] or elective percutaneous coronary intervention [PCI]) and the randomized treatment effects of low-dose aspirin (compared with placebo) and apixaban (compared with vitamin K antagonist [VKA]) on the risk of stent thrombosis. 31707833 2020
Entrez Id: 23659
Gene Symbol: PLA2G15
PLA2G15
0.100 GeneticVariation disease BEFREE During crisis, patients presented with less acute coronary syndrome (ACS - 45.5% vs. 39.9%, p < 0.001). 29601956 2020
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE What Are Optimal P2Y12 Inhibitor and Schedule of Administration in Patients With Acute Coronary Syndrome? 31645108 2020
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
0.100 AlteredExpression disease BEFREE Few studies have investigated the relationship between PCSK9 levels and the severity of coronary artery disease in patients with acute coronary syndrome; thus, we herein aimed to investigate this relationship in patients with non-ST-elevation myocardial infarction (NSTEMI) who underwent coronary angiography. 31206403 2020
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE P2Y12 inhibitors in acute coronary syndrome patients with renal dysfunction: an analysis from the RENAMI and BleeMACS projects. 31511896 2020
Entrez Id: 84680
Gene Symbol: ACCS
ACCS
0.100 Biomarker disease BEFREE We describe the incidence, timing, and characteristics of stent thrombosis and its consequences in patients with atrial fibrillation (AF) in the AUGUSTUS trial<sup>1</sup> who received a coronary stent during their qualifying admission (acute coronary syndrome [ACS] or elective percutaneous coronary intervention [PCI]) and the randomized treatment effects of low-dose aspirin (compared with placebo) and apixaban (compared with vitamin K antagonist [VKA]) on the risk of stent thrombosis. 31707833 2020
Entrez Id: 84680
Gene Symbol: ACCS
ACCS
0.100 Biomarker disease BEFREE Information on the relationship between circulating cholesteryl ester transfer protein (CETP) levels and coronary heart disease (CHD) incidence (and also, therefore, acute coronary syndrome [ACS]) is conflicting. 31504738 2020
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE We describe the incidence, timing, and characteristics of stent thrombosis and its consequences in patients with atrial fibrillation (AF) in the AUGUSTUS trial<sup>1</sup> who received a coronary stent during their qualifying admission (acute coronary syndrome [ACS] or elective percutaneous coronary intervention [PCI]) and the randomized treatment effects of low-dose aspirin (compared with placebo) and apixaban (compared with vitamin K antagonist [VKA]) on the risk of stent thrombosis. 31707833 2020
Entrez Id: 55902
Gene Symbol: ACSS2
ACSS2
0.100 GeneticVariation disease BEFREE During crisis, patients presented with less acute coronary syndrome (ACS - 45.5% vs. 39.9%, p < 0.001). 29601956 2020
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE Recently, three randomized trials reported that dual antithrombotic treatments (DATs) including non-vitamin K antagonist oral anticoagulants (NOACs) and a P2Y12 inhibitor without aspirin were associated with significantly less bleeding than vitamin K antagonist (VKA)-based triple antithrombotic therapy (TAT) in atrial fibrillation (AF) patients with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI). 31603196 2020
Entrez Id: 23659
Gene Symbol: PLA2G15
PLA2G15
0.100 Biomarker disease BEFREE Information on the relationship between circulating cholesteryl ester transfer protein (CETP) levels and coronary heart disease (CHD) incidence (and also, therefore, acute coronary syndrome [ACS]) is conflicting. 31504738 2020
Entrez Id: 23659
Gene Symbol: PLA2G15
PLA2G15
0.100 Biomarker disease BEFREE We describe the incidence, timing, and characteristics of stent thrombosis and its consequences in patients with atrial fibrillation (AF) in the AUGUSTUS trial<sup>1</sup> who received a coronary stent during their qualifying admission (acute coronary syndrome [ACS] or elective percutaneous coronary intervention [PCI]) and the randomized treatment effects of low-dose aspirin (compared with placebo) and apixaban (compared with vitamin K antagonist [VKA]) on the risk of stent thrombosis. 31707833 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.100 GeneticVariation disease BEFREE For patients with acute coronary syndrome (ACS) treated with percutaneous coronary intervention (PCI), it is unclear whether angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) are associated with reduced mortality, particularly with preserved left ventricular ejection fraction (LVEF). 31105064 2020
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE Among 36 CR and 36 non-CR acute coronary syndrome (ACS) patients, the platelet functions were evaluated by VerifyNow P2Y12 assay (turbidimetric-based optical detection) and DNA methylation levels on two fragments of the CGI from the GCK were investigated through bisulfite pyrosequencing methods. 31605429 2020
Entrez Id: 55902
Gene Symbol: ACSS2
ACSS2
0.100 Biomarker disease BEFREE Information on the relationship between circulating cholesteryl ester transfer protein (CETP) levels and coronary heart disease (CHD) incidence (and also, therefore, acute coronary syndrome [ACS]) is conflicting. 31504738 2020
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE Incidence and reasons of dual antiplatelet therapy (DAPT) discontinuation and switching between P2Y12 inhibitors in acute coronary syndrome (ACS) patients treated with a stent have been poorly studied. 31266007 2020
Entrez Id: 84680
Gene Symbol: ACCS
ACCS
0.100 GeneticVariation disease BEFREE During crisis, patients presented with less acute coronary syndrome (ACS - 45.5% vs. 39.9%, p < 0.001). 29601956 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.100 GeneticVariation disease BEFREE Genetic polymorphism of angiotensin converting enzyme and angiotensin II type 1 receptors and their impact on the outcome of acute coronary syndrome. 31195108 2020
Entrez Id: 213
Gene Symbol: ALB
ALB
0.090 AlteredExpression disease BEFREE The prognostic utility of serum albumin level as a predictor of survival in patients with acute coronary syndrome (ACS) has attracted considerable attention. 31815281 2020
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
0.080 AlteredExpression disease BEFREE Other cardiovascular complications seen in GBS patients were Increased pro-BNP(26.04%), raised troponin T levels(3.12%), acute coronary syndrome(2.08%), heart failure(2.08%) and abnormal 2D echo findings(8.33%). 31504947 2020
Entrez Id: 1071
Gene Symbol: CETP
CETP
0.070 AlteredExpression disease BEFREE Information on the relationship between circulating cholesteryl ester transfer protein (CETP) levels and coronary heart disease (CHD) incidence (and also, therefore, acute coronary syndrome [ACS]) is conflicting. 31504738 2020
Entrez Id: 4973
Gene Symbol: OLR1
OLR1
0.060 Biomarker disease BEFREE This sLOX-1 plays a key role in the pathogenesis of atherosclerosis, and elevated sLOX-1 concentrations correlate with thin or ruptured fibrous caps in patients with acute coronary syndrome. 31708514 2020
Entrez Id: 4973
Gene Symbol: OLR1
OLR1
0.060 Biomarker disease BEFREE MicroRNA-9 overexpression suppresses vulnerable atherosclerotic plaque and enhances vascular remodeling through negative regulation of the p38MAPK pathway via OLR1 in acute coronary syndrome. 31571264 2020